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(m) DNA damage foci in senescent MAFs of the indicated genotype (left, shown by 53BP1 immunofluorescence in red) and in co cultured reporter fibroblasts (right, foci also contain green 53BP1 GFP fusion protein). (n) Senescent nfkb1/ MAFs induce more DNA damage in non senescent bystander cells than senescent wt MAFs. 53BP1 GFP foci frequencies in bystander fibroblasts after the indicated times of co culture are shown.. Women Air Jordan 11

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